Semaglutide Two-Year Study Results | RxNotebook

15.2% Average Loss With Semaglutide at 104 WeeksHonest reviews of 89+ online health providers across GLP-1 weight loss, TRT, ED, hair loss, women's health, longevity, peptides, and primary care. Compare pricing, clinical oversight, and real patient experiences. 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Mean body-weight change from baseline to week 104 was −15.2% with semaglutide and −2.6% with placebo.

304 adults with obesity or overweight plus at least one weight-related comorbidity, without diabetes; 104 weeks. Read the linked peer-reviewed source for the full methodology, findings, and limitations.

Garvey et al., Nature Medicine 2022 · STEP 5