Tirzepatide After Lifestyle Program Study | RxNotebook

18.4% Additional Loss With Tirzepatide After a Lifestyle ProgramHonest reviews of 89+ online health providers across GLP-1 weight loss, TRT, ED, hair loss, women's health, longevity, peptides, and primary care. Compare pricing, clinical oversight, and real patient experiences. 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From randomization to week 72, average weight change was −18.4% with tirzepatide and +2.5% with placebo.

579 adults with obesity or overweight plus a weight-related complication, excluding diabetes, who had already lost at least 5% during a 12-week intensive lifestyle intervention; 72 weeks after a 12-week lifestyle lead-in. Read the linked peer-reviewed source for the full methodology, findings, and limitations.

Wadden et al., Nature Medicine 2023 · SURMOUNT-3