Tirzepatide vs Semaglutide: 72-Week Results | RxNotebook

20.2% Average Loss With Tirzepatide vs. 13.7% With SemaglutideHonest reviews of 89+ online health providers across GLP-1 weight loss, TRT, ED, hair loss, women's health, longevity, peptides, and primary care. Compare pricing, clinical oversight, and real patient experiences. 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Mean body-weight change was −20.2% with tirzepatide and −13.7% with semaglutide.

751 adults with obesity and without type 2 diabetes; 72 weeks. Read the linked peer-reviewed source for the full methodology, findings, and limitations.

Aronne et al., NEJM 2025 · SURMOUNT-5