TMates vs SkinnyRx (2026): Men's Health GLP-1 vs Broad Formulary
TMates and SkinnyRx both offer compounded GLP-1, but they serve different patient profiles. TMates is a men's health platform that combines GLP-1 with TRT, ED, and other men's health treatments. SkinnyRx is a GLP-1-focused platform with an unusually broad compounded formulary including oral tirzepatide, sublingual semaglutide, and orforglipron.
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TMates and SkinnyRx are both compounded GLP-1 platforms competing primarily on price. TMates is known for its flat-rate pricing model — all doses are priced the same. SkinnyRx uses a more traditional tiered pricing structure. Both use licensed pharmacy partners and require a prescriber consult.
TMates' flat-rate model is increasingly cost-effective as you escalate to higher doses. SkinnyRx may be more competitive at entry-level doses. Both are solid low-cost options for compounded GLP-1 access — compare pricing at your expected maintenance dose before committing.
TMates
Flat-rate compounded GLP-1s plus brand-name Wegovy and Zepbound, with all dosages priced the same.
SkinnyRx
Clinician-guided GLP-1 platform with both compounded and brand-name access plus overnight shipping.
Side-by-Side Comparison
| Attribute | TMates | SkinnyRx |
|---|---|---|
| Program Fee | Included in monthly plan | Included in monthly plan |
| Medication From | From $80 – $299/mo | From $99 – $199/mo |
| Editor Score | 4.6 / 5 | 4.3 / 5 |
| Primary Category | GLP-1 Weight Loss | GLP-1 Weight Loss |
| FDA Brand-Name Access | Wegovy, Zepbound | Wegovy, Zepbound, Ozempic, Mounjaro, Foundayo |
| Compounded Options | 2 compounds | 4 compounds |
| Adjacent Categories | Erectile Dysfunction, Longevity & NAD+ | GLP-1 Weight Loss |
The Verdict
TMates is the better pick for men who want to manage GLP-1 and other men's health conditions (TRT, ED) on a single platform. SkinnyRx is the better pick for patients who want the widest range of GLP-1 delivery formats (oral, sublingual, and injectable) at competitive prices.
Frequently Asked Questions
Does TMates offer oral GLP-1?
TMates focuses primarily on injectable compounded GLP-1. Confirm the exact oral formulation, pharmacy, and availability directly with any provider.
Does SkinnyRx offer TRT?
SkinnyRx is a GLP-1-focused platform and does not offer TRT. TMates covers TRT, ED, and other men's health conditions alongside GLP-1.
Which is cheaper?
SkinnyRx starts at $149.25/mo for compounded injectable plans. TMates pricing is comparable for GLP-1; the total cost depends on whether you add TRT or ED treatments.