Independent · Reader-Supported · Editorially Reviewed
§ Telehealth Basics

Tadalafil

A PDE5 inhibitor (Cialis) for erectile dysfunction and BPH; longer-acting than sildenafil. Available as daily 5 mg or as-needed 10-20 mg from online ED

Fact-checked 12 May 2026Plain-English Reference

Tadalafil's 17-hour half-life makes it useful as a daily low-dose (2.5-5 mg) treatment, removing the timing pressure of on-demand dosing. It is also FDA-approved for benign prostatic hyperplasia. Side-effect profile is broadly similar to sildenafil with somewhat more myalgia.

§ Where Tadalafil Comes Up