Reader-Supported · Editorially Reviewed
§ Brand Review · GLP-1 Weight Loss

He & She MD Review

Multi-category telehealth platform advertising semaglutide from $139/month, subject to clinical eligibility and confirmation of final terms.

Last reviewed August 2026
2 studies cited
Fact-checked 28 August 2026Last updated 28 August 2026From $139 – $139/moEditor Score 4.0 / 5

We may earn a commission through provider links. Matching affiliate offers and editorial priorities affect inclusion and suggested order in commercial guides. Scores are not clinical endorsements. Disclosure · Methodology

Quick Verdict

Multi-category telehealth platform advertising semaglutide from $139/month, subject to clinical eligibility and confirmation of final terms.

Who it's for: He & She MD may suit adults who prefer a single online-care platform spanning weight management, hormones, longevity, hair growth and sexual health. Its reviewed homepage describes a brief medical quiz followed by licensed-clinician review, with medication shipped if appropriate. The site lists injectable and oral semaglutide and tirzepatide options alongside brand-name pathways, but treatment availability, clinical eligibility and costs can vary. The displayed injectable semaglutide promotion began at $139 per month at review, so readers should confirm whether that amount is introductory, which dose it covers, and whether any services are billed separately.

Bottom line: He & She MD has a broad online treatment menu and a visible semaglutide starting price, but the wide catalog makes an all-in checkout review important. Confirm the exact medication, recurring price, dispensing pharmacy, refill process and cancellation terms before starting. Compounded medications are not FDA-approved finished drugs and should not be treated as interchangeable with FDA-approved products.

Pros
  • Multiple GLP-1 formats and related care categories listed
  • Licensed-clinician review and direct medication delivery described
  • Published injectable semaglutide starting promotion
Cons
  • Published starting price may not reflect all medication formats or doses
  • All-in recurring fees and renewal terms require confirmation
  • Compounded medications are not FDA-approved finished drugs

Pros & Cons In Detail

Multiple GLP-1 formats and related care categories listed
In practice this is one of the differentiators that pushes He & She MD's editor score above the category median.
Licensed-clinician review and direct medication delivery described
Active clinical oversight means dose changes, side-effect management, and labs are handled by a licensed prescriber rather than a generic intake form.
Published injectable semaglutide starting promotion
In practice this is one of the differentiators that pushes He & She MD's editor score above the category median.
Published starting price may not reflect all medication formats or doses
Cost is in line with category leaders, not below them. readers shopping primarily on monthly out-of-pocket should weigh the alternatives in the listicle.
All-in recurring fees and renewal terms require confirmation
It's a real trade-off worth knowing about before you commit, even if it isn't a deal-breaker on its own.
Compounded medications are not FDA-approved finished drugs
It's a real trade-off worth knowing about before you commit, even if it isn't a deal-breaker on its own.

He & She MD Pricing

Telehealth ads often advertise a low headline price that's the clinic's program fee, not the medication. Here's how the two line items break down at He & She MD.

Program / Membership FeeIncluded in advertised program price
Medication Cost (From)From $139 – $139/mo
What This Means For You

He & She MD advertised injectable semaglutide from $139/month on the reviewed page. Its page also lists multiple treatment categories; confirm the medication, dose, all-in recurring charge, pharmacy, refill terms and cancellation policy before enrollment.

Who He & She MD Is For

He & She MD may suit adults who prefer a single online-care platform spanning weight management, hormones, longevity, hair growth and sexual health. Its reviewed homepage describes a brief medical quiz followed by licensed-clinician review, with medication shipped if appropriate. The site lists injectable and oral semaglutide and tirzepatide options alongside brand-name pathways, but treatment availability, clinical eligibility and costs can vary. The displayed injectable semaglutide promotion began at $139 per month at review, so readers should confirm whether that amount is introductory, which dose it covers, and whether any services are billed separately.

How He & She MD Markets Itself

Adults seeking one telehealth platform for GLP-1 weight management and related hormone, longevity, hair, or sexual-health care.

Signature Programs

  • ›Weight-loss medication evaluation
  • ›GLP-1 injections and oral options listed
  • ›NAD+ and sermorelin programs
  • ›Hormone, hair and sexual-health categories

Medication Formulary

FDA-Approved Access
OzempicZepbound
Full Formulary
semaglutide injectiontirzepatide injectionoral semaglutideoral tirzepatidenad+sermorelinestradioltestosterone

The Bottom Line

He & She MD has a broad online treatment menu and a visible semaglutide starting price, but the wide catalog makes an all-in checkout review important. Confirm the exact medication, recurring price, dispensing pharmacy, refill process and cancellation terms before starting. Compounded medications are not FDA-approved finished drugs and should not be treated as interchangeable with FDA-approved products.

With an editor score of 4.0 / 5 across cost, experience, and trust, He & She MD is one of the specialty options in the glp-1 weight loss category we cover.

See how He & She MD compares in our full glp-1 weight loss rankings. Our methodology explains how we score each provider.

§ FAQ

Frequently Asked Questions

References — Clinical Studies
  1. Wilding et al., NEJM 2021 (STEP 1) · Semaglutide 2.4 mg produced 14.9% mean weight loss versus 2.4% with placebo at 68 weeks in the STEP 1 trial.
  2. Jastreboff et al., NEJM 2022 (SURMOUNT-1) · Tirzepatide 15 mg produced 20.9% mean weight loss versus 3.1% with placebo at 72 weeks in SURMOUNT-1.

RxNotebook is an editorial publication, not a medical practice. We are not affiliated with the cited studies; source material does not endorse the providers shown. This is general information, not medical advice.

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