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§ Brand Review · GLP-1 Weight Loss

Willow Review

Premium GLP-1 clinic with a needle-free sublingual semaglutide tablet option.

Last reviewed July 2026
4 studies cited
Fact-checked 18 July 2026Last updated 15 June 2026From $299 – $549/moEditor Score 4.0 / 5Trustpilot 3.9 · Average

Reader-supported, we may earn a commission through links on this site. Rankings are editorially independent. Disclosure · Methodology

Quick Verdict

Premium GLP-1 clinic with a needle-free sublingual semaglutide tablet option.

Who it's for: Willow is best suited to readers who specifically want a sublingual semaglutide tablet alternative to injections and are willing to pay a premium monthly rate for unlimited physician access and two-day shipping. The sublingual tablet option is the clearest differentiator — it is one of the few telehealth platforms that offers oral semaglutide as a primary delivery format rather than an add-on.

Bottom line: A premium-priced clinic that earns its rate through the sublingual tablet option and unlimited messaging. Most buyers can find compounded injections cheaper elsewhere. Most buyers can find compounded GLP-1 for less elsewhere; Willow's premium is justified primarily by the sublingual tablet option and the unlimited messaging model.

Pros
  • Sublingual semaglutide tablets are rare
  • Same-day approval and two-day shipping
  • Unlimited physician messaging
Cons
  • Highest monthly entry price in the category
  • Compounded only, no brand-name option
  • Sublingual GLP-1 absorption is less validated than injection

Pros & Cons In Detail

Sublingual semaglutide tablets are rare
In practice this is one of the differentiators that pushes Willow's editor score above the category median.
Same-day approval and two-day shipping
Reliable shipping is the most underrated quality signal in telehealth. patients who switch providers usually do so because of refill timing, not price.
Unlimited physician messaging
In practice this is one of the differentiators that pushes Willow's editor score above the category median.
Highest monthly entry price in the category
Cost is in line with category leaders, not below them. readers shopping primarily on monthly out-of-pocket should weigh the alternatives in the listicle.
Compounded only, no brand-name option
It's a real trade-off worth knowing about before you commit, even if it isn't a deal-breaker on its own.
Sublingual GLP-1 absorption is less validated than injection
It's a real trade-off worth knowing about before you commit, even if it isn't a deal-breaker on its own.

Willow Pricing

Telehealth ads often advertise a low headline price that's the clinic's program fee, not the medication. Here's how the two line items break down at Willow.

Program / Membership FeeIncluded in monthly plan
Medication Cost (From)From $299 – $549/mo
What This Means For You

Willow bundles physician oversight, medication, free two-day shipping, and unlimited messaging into one premium monthly fee. There is no brand-name medication option and no insurance billing.

Who Willow Is For

Willow is best suited to readers who specifically want a sublingual semaglutide tablet alternative to injections and are willing to pay a premium monthly rate for unlimited physician access and two-day shipping. The sublingual tablet option is the clearest differentiator — it is one of the few telehealth platforms that offers oral semaglutide as a primary delivery format rather than an add-on.

How Willow Markets Itself

Needle-averse adults who want a premium-priced GLP-1 program with sublingual semaglutide tablets and unlimited physician access.

Signature Programs

  • ›Compounded semaglutide injection
  • ›Sublingual semaglutide tablets
  • ›Compounded tirzepatide injection

Medication Formulary

Full Formulary
compounded semaglutidecompounded sublingual semaglutidecompounded semaglutide tabletsoral glp-1 pillscompounded tirzepatidenad+

The Bottom Line

A premium-priced clinic that earns its rate through the sublingual tablet option and unlimited messaging. Most buyers can find compounded injections cheaper elsewhere. Most buyers can find compounded GLP-1 for less elsewhere; Willow's premium is justified primarily by the sublingual tablet option and the unlimited messaging model.

With an editor score of 4.0 / 5 across cost, experience, and trust, Willow is one of the specialty options in the glp-1 weight loss category we cover.

See how Willow compares in our full glp-1 weight loss rankings, or read the Best Telehealth GLP-1 Providers guide. Our methodology explains how we score each provider.

§ FAQ

Frequently Asked Questions

References
  1. Wilding et al., NEJM 2021 (STEP 1) · Semaglutide 2.4 mg produced 14.9% mean weight loss vs 2.4% placebo at 68 weeks in the STEP 1 trial.
  2. FDA Federal Register 2024 (Semaglutide shortage end) · FDA removed semaglutide from the drug shortage list in October 2024, ending the legal basis for compounding.
  3. Jastreboff et al., NEJM 2022 (SURMOUNT-1) · Tirzepatide 15 mg produced 20.9% mean weight loss vs 3.1% placebo at 72 weeks in SURMOUNT-1.
  4. FDA Federal Register 2024 (Tirzepatide shortage end) · FDA removed tirzepatide from the drug shortage list in October 2024.

RxNotebook is an editorial publication. Citations point to peer-reviewed journals, FDA labeling, and clinical society guidelines. We are not affiliated with the studies cited above. This page is for general information and is not medical advice.

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Also Competes With

Willow also operates in Longevity & NAD+. Here are other providers in those spaces:

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