Willow Review
Premium GLP-1 clinic with a needle-free sublingual semaglutide tablet option.
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Quick Verdict
Premium GLP-1 clinic with a needle-free sublingual semaglutide tablet option.
Who it's for: Willow is best suited to readers who specifically want a sublingual semaglutide tablet alternative to injections and are willing to pay a premium monthly rate for unlimited physician access and two-day shipping. The sublingual tablet option is the clearest differentiator — it is one of the few telehealth platforms that offers oral semaglutide as a primary delivery format rather than an add-on.
Bottom line: A premium-priced clinic that earns its rate through the sublingual tablet option and unlimited messaging. Most buyers can find compounded injections cheaper elsewhere. Most buyers can find compounded GLP-1 for less elsewhere; Willow's premium is justified primarily by the sublingual tablet option and the unlimited messaging model.
- Sublingual semaglutide tablets are rare
- Same-day approval and two-day shipping
- Unlimited physician messaging
- Highest monthly entry price in the category
- Compounded only, no brand-name option
- Sublingual GLP-1 absorption is less validated than injection
Pros & Cons In Detail
Willow Pricing
Telehealth ads often advertise a low headline price that's the clinic's program fee, not the medication. Here's how the two line items break down at Willow.
| Program / Membership Fee | Included in monthly plan |
| Medication Cost (From) | From $299 – $549/mo |
Willow bundles physician oversight, medication, free two-day shipping, and unlimited messaging into one premium monthly fee. There is no brand-name medication option and no insurance billing.
Who Willow Is For
Willow is best suited to readers who specifically want a sublingual semaglutide tablet alternative to injections and are willing to pay a premium monthly rate for unlimited physician access and two-day shipping. The sublingual tablet option is the clearest differentiator — it is one of the few telehealth platforms that offers oral semaglutide as a primary delivery format rather than an add-on.
Needle-averse adults who want a premium-priced GLP-1 program with sublingual semaglutide tablets and unlimited physician access.
Signature Programs
- ›Compounded semaglutide injection
- ›Sublingual semaglutide tablets
- ›Compounded tirzepatide injection
Medication Formulary
The Bottom Line
A premium-priced clinic that earns its rate through the sublingual tablet option and unlimited messaging. Most buyers can find compounded injections cheaper elsewhere. Most buyers can find compounded GLP-1 for less elsewhere; Willow's premium is justified primarily by the sublingual tablet option and the unlimited messaging model.
With an editor score of 4.0 / 5 across cost, experience, and trust, Willow is one of the specialty options in the glp-1 weight loss category we cover.
See how Willow compares in our full glp-1 weight loss rankings, or read the Best Telehealth GLP-1 Providers guide. Our methodology explains how we score each provider.
Frequently Asked Questions
- Wilding et al., NEJM 2021 (STEP 1) · Semaglutide 2.4 mg produced 14.9% mean weight loss vs 2.4% placebo at 68 weeks in the STEP 1 trial.
- FDA Federal Register 2024 (Semaglutide shortage end) · FDA removed semaglutide from the drug shortage list in October 2024, ending the legal basis for compounding.
- Jastreboff et al., NEJM 2022 (SURMOUNT-1) · Tirzepatide 15 mg produced 20.9% mean weight loss vs 3.1% placebo at 72 weeks in SURMOUNT-1.
- FDA Federal Register 2024 (Tirzepatide shortage end) · FDA removed tirzepatide from the drug shortage list in October 2024.
RxNotebook is an editorial publication. Citations point to peer-reviewed journals, FDA labeling, and clinical society guidelines. We are not affiliated with the studies cited above. This page is for general information and is not medical advice.
Alternatives To Willow
Also Competes With
Willow also operates in Longevity & NAD+. Here are other providers in those spaces: