NewSelf vs Trimi (2026): Which Budget GLP-1 Clinic Wins on Price?
NewSelf and Trimi are two of the most aggressively priced compounded GLP-1 clinics in 2026, both offering flat-dose pricing where all dosage tiers cost the same monthly rate. NewSelf starts at $99.97/mo for semaglutide with a 3-month supply shipped upfront. Trimi starts at $99/mo with a flat rate at every dose tier and a strong Trustpilot score of 4.7.
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NewSelf's core differentiator is its flat-dose pricing model: compounded semaglutide costs $99.97/mo at every dose tier, from the 0.25 mg starting dose through the 2.4 mg maintenance dose. Tirzepatide starts at $144.49/mo with the same flat-rate structure. NewSelf ships a 3-month supply upfront, which eliminates refill delays and reduces the per-unit cost. The platform works with 1,000+ board-certified physicians across all 50 states and offers overnight shipping. Some customers have flagged customer service responsiveness and billing confusion on multi-month plans.
Trimi is a flat-rate GLP-1 clinic with a strong reputation — Trustpilot 4.7 from a large review base. Its $99/mo flat rate at every dose tier is comparable to NewSelf's semaglutide pricing, and Trimi's higher Trustpilot score suggests a more consistent patient experience. Trimi also offers tirzepatide at a flat rate, making it a strong competitor across both GLP-1 options. For patients who prioritize a proven track record over the lowest possible sticker price, Trimi is the stronger choice.
NewSelf
Industry-low flat-dose pricing on compounded semaglutide and tirzepatide — all dosages, one price, no membership fee.
Trimi
Flat-rate compounded GLP-1 clinic — semaglutide from $99/mo and tirzepatide from $125/mo at every dose, with a 6-month money-back guarantee.
Side-by-Side Comparison
| Attribute | NewSelf | Trimi |
|---|---|---|
| Program Fee | No membership fee | Included in monthly plan |
| Medication From | From $99 – $224/mo | From $99 – $125/mo |
| Editor Score | 4.6 / 5 | 4.8 / 5 |
| Primary Category | GLP-1 Weight Loss | GLP-1 Weight Loss |
| FDA Brand-Name Access | Compounded only | Compounded only |
| Compounded Options | 2 compounds | 2 compounds |
| Adjacent Categories | GLP-1 Weight Loss |
The Verdict
Both NewSelf and Trimi offer flat-dose pricing starting at $99/mo for compounded semaglutide — making them the two cheapest options in our network. Trimi wins on Trustpilot score (4.7 vs 4.5) and patient experience consistency. NewSelf wins on the 3-month upfront supply model and slightly broader physician network. For most budget-focused patients, Trimi is the safer default; NewSelf is worth considering if the upfront supply model appeals.
Frequently Asked Questions
Is NewSelf or Trimi cheaper?
Both start at $99/mo for compounded semaglutide with flat-dose pricing. NewSelf's tirzepatide starts at $144.49/mo; Trimi's tirzepatide is also flat-rate. The pricing is effectively equivalent — the differentiator is patient experience, not price.
What is flat-dose pricing?
Flat-dose pricing means you pay the same monthly rate regardless of which dose tier you're on. Most GLP-1 clinics charge more as your dose escalates (e.g. $149/mo at 0.25 mg, $249/mo at 1 mg). Flat-dose pricing eliminates this increase, making long-term costs more predictable.
Which has better reviews — NewSelf or Trimi?
Trimi has a higher Trustpilot score (4.7 vs 4.5 for NewSelf) and a larger review base. NewSelf has over 2,000 Trustpilot reviews but some flag customer service responsiveness. Trimi's reviews are more consistently positive.